Does Depression Specifically Increase Cardiovascular Mortality? -- VINKERS and van der MAST 165 (9): 1204 -- Am J Psychiatry

DAVID J. VINKERS, M.D., Ph.D., ROOS C. MAST, M.D., Ph.D. Leiden, the Netherlands To the Editor: We study with concern the interpret conducted by Paul G. Surtees, Ph.D., Apr 2008 subject of the Diary (1). The authors reported that dominant depression was associated with increased affection disease mortality in almost 20,000 individuals between the ages of 41 and 80 oldness who participated in the Norfolk, U.K.

European Prospective Examination Into Cancer (EPIC-Norfolk) Study. This finding suggests that depression specifically increases cardiovascular mortality by cardiovascular mechanisms. However, Dr. Surtees et al. Earlier findings from the EPIC-Norfolk glance at showed that both cardiovascular and noncardiovascular mortality are increased among individuals with wick self-reported intellectual health (2) and pathetic solution of coherence (3).

When noncardiovascular mortality is and increased among depressed individuals, it is viable that unhealthy behaviour and a lifestyle inherent to depression, rather than cardiovascular mechanisms, clarify the increased mortality risk associated with depression (4). Footnotes The authors announcement no competing interests. This dispatch (doi: 10.1176 appi.ajp.2008.08040523) was regular for tome in May 2008.

References Surtees PG, Wainwright NW, Luben RN, Wareham NJ, Bingham SA, Khaw KT: Depression and ischemic passion disease mortality: evidence from the EPIC-Norfolk United Field Prospective Cohort Study. Am J Psychiatry 2008; 165:515-523 Summary For love Abundant Issue Myint PK, Luben RN, Surtees PG, Wainwright NW, Welch AA, Bingham SA, Wareham NJ, Smith RD, Harvey IM, Khaw KT: Self-reported mental health-related attribute of high spirits and mortality in men and women in the European Prospective Interrogation into Cancer (EPIC-Norfolk): a prospective population study.

Psychosom Med 2007; 69:410-414 Abstract Unpaid Comprehensive Words Surtees P, Wainwright N, Luben R, Khaw KT, Age N: Notion of coherence and mortality in men and women in the EPIC-Norfolk United Province Prospective Cohort Study. Am J Epidemiol 2003; 158:1202-1209 Abstract Unrestrained Adequate Contents Vinkers DJ, Stek ML, Gussekloo J, motorcar der Mast RC, Westendorp RG: Does depression in gray-haired interval development one shot cardiovascular mortality?