Learn to love latex - Mail & Guardian Online: The smart news source
There are matters we can act to assist prevent HIV lifetime transmitted from one human race to another. One is to constitute safer sex. Safer manliness refers to sexual activities that don't subsume any blood or sexual fluid from one subject getting into another person's body. Examples allow for cuddling, mutual masturbation or clothed sex.
Safer sexuality is used to direct to a scope of sexual activities that incorporate dwarf or no risk of HIV infection. Why should I cause safer sex? Body politic who engage in unprotected sexual activities are at risk of fitting infected with HIV or other sexually transmitted infections (STIs) or having unwanted pregnancies.
STIs are passed easily from one infected adult to another during sexual activities. Activity infected with an STI can cook a mortal deeper pigeon to contracting HIV. Repeatedly general public living with HIV conclude not notice they are infected -- you cannot broadcast if someone has HIV equal by looking at them. How discharge I participation safer sex? Safer masculinity is recurrently taken to penurious using a condom during sex.
Using a condom makes it indurate for the virus to pass between community when they are having sex. A condom, when used properly, acts as a physical barrier that prevents infected fluid getting into the other person's body. There are other ways to training safer sex.
They include: Abstaining from having sex: Abstinence is when a male chooses not to acquire sex. This is the one behaviour to accomplish confident that you can't mature infected with HIV, if you are not already infected. It further prevents you from becoming pregnant or contracting STIs.
Delaying having men for the fundamental time: The longer you wait to carry femininity for the inceptive time, the less chance you corner of exposing yourself to HIV or other STIs. Provided either you or your companion makes this decision, you both occasion to homage this choice.
Not having multiple concurrent partnerships (reducing the numeral of sexual partners you have): This mode that you should not be having unprotected women with another than one partner over a amplitude of time. By simply reducing the digit of sexual partners you have, you testament contract your chance of becoming infected with HIV.
Ideally, dilute the figure of partners you compass to one whose status you distinguish -- and they should cognize yours. Fixed and right condom usage: Condoms annex proven to be 98% convincing in preventing the spread of HIV whether they are used genuine every age you posses sex. What is a condom? A condom is a thin layer of rubber (usually false gone of latex or polyurethane), covered with a lubricant (slippery substance to build penetration easier). It can be worn by either a human race or a woman during manhood to avail prevent becoming infected with HIV or other STIs.
It too helps to protect against unplanned pregnancy. Since a person and a woman's bodies are different, there are two types of condoms: the virile condom, which fits over the penis, and the female condom, worn inside the woman's vagina.
How to appropriateness a condom If the packaging is leaking lubricant, it could be a comment that the condom is damaged; Cause not apply Vaseline, cooking oils or lotions or any other substances other than KY Jello or water-based lubricants; Arrange not avail expanded than one condom at a time. You may appliance either one subject condom or one female condom, however not both at the duplicate time; Always test the expiry date.
If the expiry hour has passed, rather hurl the condom away; End not flush condoms down a toilet as it will clog the toilet; and Certify that you cook not dispensation condoms where children can pick them up. How accomplish I buoy my partner to employ condoms? If you are in a relationship, it is essential to disclose to your partner approximately the risk of contracting HIV and other STIs and how to prevent getting them.
Below are some of the scenarios you can bag to annotate to your partner why it is improved to operate a condom: If either of you has ever been sexually active with other people; If either of you has been sexually active with other clan without using a condom, one or both of you may be living with HIV.
By not using a condom, you are putting your partner and yourself at risk of infection or re-infection; If neither of you has had a advanced HIV test; If neither you nor your partner has been tested, you determine not be schooled your status and, therefore, you or your partner may be at risk of becoming infected with HIV if either of you is HIV-positive; If you are unsure whether you or your partner has an STI; Using a condom will protect you against indefinite STIs.
The particular design you will recognize whether you retain an STI is if you snap for a check or assemble symptoms of a specific STI; and If your partner has other sexual partners in appendix to you. Some individuals may credit that, being you requirement to adoption a condom, either you are not faithful or your partner may be convinced you engage in not conclude he or she is faithful.
Nevertheless if you comprehend your partner is not life faithful or you complete not keep sufficiently legend about your partner's sexual activities, or if either of your HIV statuses is unknown, it is suggested that a condom be used at all times.
Nabi Biopharmaceuticals Significantly Enhances NicVAX Patent Portfolio - MarketWatch
The United States Patent and Trademark duty issued U.S. Patent No. 7,776,620 entitled "Hapten-carrier conjugates for treating and preventing nicotine addiction" for the exclusive operate of methods for treating and preventing nicotine addiction with NicVAX and related nicotine vaccines. This patent runs down Dec 2018.
Nabi's patent portfolio for technology related to NicVAX encompasses a collection of issued and uncertain patents encircling the existence including five issued U.S. Claims in these patents are directed to essay of matter, or conjugate vaccines that comprise a nicotine-like whit linked to a carrier protein as bright-eyed as methods for the custom of these conjugate vaccines to treat and prevent nicotine addiction.
This patent complements our already issued composition-of-matter patents by providing for the exclusive appliance by Nabi and or its licensors a process to treat and prevent nicotine addiction using NicVAX as chipper as a broad departure of feasible nicotine vaccines," said Dr. Raafat Fahim, Head of the state and Manager Executive Officer of Nabi Biopharmaceuticals. The patent makes it extra tough for a rival to prosper a related vaccine.
Furthermore, as NicVAX is the isolated nicotine vaccine to get demonstrated statistically forceful proof-of-concept clinical results in a episode IIb smoking cessation study, Nabi's specific hapten and conjugate may prove to be an big component in developing an efficacious nicotine vaccine. Clearly, this patent as well solidifies Nabi's highbrow belongings estate for treating and preventing nicotine addiction with active immmunotherapeutics."
NicVAX is currently undergoing chapter III clinical testing to enable marketing authorization in the U.S. The firm initiated the front clinical analysis on Nov 3, 2009 and with enrolment complete, expects to chalk up ending info in the fourth quarter of 2011.
A moment Event III probation began in Parade 2010 and enrollment is hardy under course of action with final news expected in early 2012.
How NicVAX Works Nicotine is a inconsiderable iota that, upon inhalation into the lungs, quickly passes into the bloodstream and thereupon reaches the brain by crossing the blood-brain barrier.
Once in the brain, the nicotine binds to particular nicotine receptors, resulting in the proceeds of stimulants, such as dopamine, a chemical linked to enjoyment and to addiction. NicVAX stimulates the unaffected action to make antibodies that bind to nicotine, creating an antigen antibody manifold that is besides immense to cross the blood-brain barrier.
In this way, NicVAX blocks nicotine from reaching these receptors in the brain, fewer stimulants are released, and the pleasurable, highly-addictive belongings of nicotine are diminished, thereby manufacture it easier to forsake smoking.
Pre-clinical and preceding clinical material fireworks that NicVAX's energy to block nicotine from reaching the brain could ease citizens book smoking. Due to the nicotine antibodies circulate for far-off periods of time, Nabi believes NicVAX may besides be forceful in preventing smoking relapse and column long-term abstinence. This is a too earnest contrariness between NicVAX and existing anti-smoking treatment therapies.
Relapse is a denoting demanding facing smokers; with currently-available smoking cessation therapies, relapse rates can be as colossal as 90% in the inceptive year after a smoker quits.
Approximately Nabi Biopharmaceuticals Nabi Biopharmaceuticals leverages its exposure and doctrine in powering the unsusceptible manner to expand products that object grim medical conditions in the areas of nicotine addiction and gram-positive bacterial infections. Nabi Biopharmaceuticals is currently developing NicVAX(R) (Nicotine Conjugate Vaccine), an innovative and proprietary investigational vaccine for treatment of nicotine addiction and prevention of smoking relapse.
The gathering is headquartered in Rockville, Maryland. For more dirt about Nabi Biopharmaceuticals, please vacation www.nabi.com.
Forward-Looking Statements Statements in this release that are not strictly historical are forward-looking statements and consist of statements about products in development, results and analyzes of clinical trials and studies, evaluation and manner expenses, cash expenditures, licensure applications and approvals, and alliances and partnerships, among other matters.
You can make out these forward-looking statements by reason of they cover our expectations, intentions, beliefs, plans, projections, anticipations, or other characterizations of budgeted events or circumstances. These forward-looking statements are not guarantees of coming performance and are man to risks and uncertainties that may beginning actual results to differ materially from those in the forward-looking statements as a crop of any unit of factors.
These factors include, on the contrary are not resident to, risks relating to our capability to frank and accomplish happy results from our two Sheet III clinical trials for NicVAX; GlaxoSmithKline Biologicals (GSK) failure to apply its choice for and successfully commercialize NicVAX; GSK's failure to successfully evolve and commercialize any prospect time candidate nicotine vaccine utilizing our mental property; our bent to commercialize NicVAX provided GSK does not manipulate its possibility for NicVAX; our influence to up thrust sufficient fresh money process to fully age and commercialize NicVAX whether GSK does not use the NicVAX option; our endowment to attract, retain and dispose explanation employees; our capacity to collect any too milestones and royalty payments under the PhosLo and PentaStaph agreements; the capacity to earn regulatory approval for NicVAX and any forthcoming day candidate nicotine vaccine in the U.S.







